I’m currently a post-doctoral fellow in Department of Pathology under supervision of Dr. Jose Otero. Our laboratory investigates morphology and neuroanatomy focused to understand relation between cognitive decline and brain irradiation used to treat brain cancers. In this context, I have been studying role of cyclin A2 in the rRNA regulation and aging hippocampus. Abnormalities in RNA dynamics can trigger deleterious process and accumulation of misfolded proteins which leads to neurodegenerative disorders. In my Ph.D. thesis, I studied the TGF beta pathway contribution to the adipose tissue remodeling in cancer cachexia. I obtained my Ph.D. and Master’s degree in Sciences, both with concentrated area in Cell and Tissue Biology, from the University of Sao Paulo, the most prestigious University in Brazil. I have full degree in Physical Education with teacher training from the Metropolitan United Faculty (FMU), a degree similar to Rehabilitation Sciences in the United States.

Department of Pathology
4170 Graves Hall
333 W 10th Avenue
Columbus, OH 43210
Michele.Alves@osumc.edu